Witryna4 mar 2024 · INTRODUCTION — Immune checkpoint inhibitors (ICIs) are the most commonly used type of cancer immunotherapy but can cause a number of immune-related adverse events (irAEs), including a variety of rheumatologic manifestations. The irAEs result from damage that occurs due to immune activation and inflammation … Witryna16 lis 2024 · Commentary on « Ipilimumab induced vasculitis » by Padda A. et al., J Immunother Cancer. 2024;6:12. The authors diagnosed a small vessel vasculitis following treatment with anti-CTLA-4 (ipilimumab) for a resected stage III B/C melanoma. We report a similar case of acral vasculitis occurring with a combination of anti-CTLA …
16. Checking in with novel cancer therapies: a case of immunotherapy …
WitrynaCancer immunotherapy significantly contributed to an improvement in the prognosis of cancer patients. Immunotherapy, including human epidermal growth factor receptor 2 (HER2)-targeted therapies, immune checkpoint inhibitors (ICI), and chimeric antigen receptor-modified T (CAR-T), share the characteristic to exploit the capabilities of the … Witryna9 sie 2024 · Emerging data show that the function of blood vessels associated with tumors is critical in the response to these immunotherapies ( 1, 2 ). The vasculature in tumors is abnormal, which impairs blood flow and limits the delivery of oxygen, nutrients, and therapeutics, including antibodies and immune cells ( 3) (see the figure). greetings from richmond va
Mast Cells and Resistance to Immunotherapy in Cancer
Witryna19 gru 2024 · Commentary on « Cerebral vasculitis mimicking intracranial metastatic progression of lung cancer during PD-1 blockade » by Läubli H et al., J Immunother … Witryna3 sty 2024 · A wide range of cancer immunotherapy approaches has been developed including non-specific immune-stimulants such as cytokines, cancer vaccines, immune checkpoint inhibitors (ICIs), and adoptive T cell therapy. Among them, ICIs are the most commonly used and intensively studied. Since 2011, these drugs have received … Witryna15 maj 2024 · Giant cell arteritis (GCA) is a granulomatous vasculitis of the aorta and its medium-sized branch vessels. CD4 T cells, macrophages, and dendritic cells (DCs) build granulomatous infiltrates that injure the vessel wall and elicit a maladaptive response to injury. Pathological consequences include fragmentation of elastic membranes, … greetings from postcard tutorial